Apriso Cost-Saving Options Manufacturer Coupons Discount Cards And Patient Assistance Programs

Oct. 17, 2025, 4:34 a.m.

Tags: apriso

Apriso is a medication used to treat ulcerative colitis in adults, and for many patients, the cost of this prescription can be a concern. While the provided source material does not specifically mention free samples of Apriso, there are several cost-saving options available to help make this medication more affordable. This article explores the various assistance programs, manufacturer coupons, and discount cards that may reduce out-of-pocket expenses for Apriso.

What is Apriso?

Apriso is the brand name for mesalamine, available as an extended-release oral capsule in a 375 mg dosage. It is classified as an aminosalicylate medication used to treat ulcerative colitis (UC) in adults. The exact mechanism of action is not fully understood, but it appears to work within the bowels to reduce gut inflammation, which helps alleviate symptoms of UC.

Apriso is typically taken as a 1.5 g dose once daily in the morning, which corresponds to four 0.375 g capsules. When used for FDA-licensed indications, Apriso is considered a safe and effective treatment. However, as with all medications, it may cause unwanted side effects. Patients should discuss potential side effects with their healthcare provider to ensure the medication is appropriate for them.

Common side effects of Apriso include headache, stomach pain, nausea, diarrhea, and indigestion. Serious side effects are rare but may include worsening UC symptoms, kidney problems, liver problems, allergic reactions, or severe skin reactions. Patients should contact their healthcare provider immediately if they experience any of these serious side effects.

Apriso should not be taken by individuals with hypersensitivity to salicylates, aminosalicylates, or any component of the capsules. Additionally, certain medications may interact with Apriso, so patients should inform their healthcare provider about all other medications they are taking.

Manufacturer Coupon Programs

Historically, Salix Pharmaceuticals offered a manufacturer coupon program for Apriso that provided significant savings to eligible patients. According to the available information, this program offered eligible insured patients $0 co-pay for their first Apriso prescription. For subsequent refills, patients would pay no more than $10, with the manufacturer covering the remaining co-pay or out-of-pocket expense up to a maximum of $100 per use. The maximum benefit for the first fill was $110.

However, the source material indicates that this specific manufacturer offer has ended. Despite this, other manufacturer coupon options may still be available. According to one source, there are manufacturer coupons for Apriso in 2025 where patients pay no more than $25, with the savings card covering up to $100 off the prescription after the initial payment.

To access these manufacturer coupons, patients typically need to fill out information online to print out the coupon or receive a savings card. The card is usually permanent and arrives by mail within 7-14 business days. When filling a prescription at a pharmacy, patients present this card to receive the discount.

The effectiveness of these coupons depends on the specific terms and the patient's insurance coverage. For example, if a patient's co-pay or retail cost exceeds $125, they would pay only $25, with the card covering $100. If the cost exceeds $80, the patient pays the first $25, and the card covers $55. The retail price for 60 capsules of Apriso 0.375g ranges from $180.00 to $190.00.

Apriso Discount Cards

In addition to manufacturer coupons, a reusable discount card is available for Apriso that can save patients up to 75% off the retail price of their medication. This discount card is described as ideal for people without prescription coverage or for those whose medication is not covered by insurance.

The card is accepted at over 63,000 pharmacies, including all major chains such as Walmart, CVS Pharmacy, Publix, Walgreens, and Rite-Aid. While the discount is generally consistent across pharmacies, there may be slight variations in pricing between different locations.

One advantage of this discount card is that everyone can qualify, regardless of insurance status or income level. To obtain the card, patients typically need to follow a link to the manufacturer's website and complete a simple enrollment process. Once enrolled, they can present the card at the pharmacy when filling their prescription to receive the discount.

The savings achieved through this card can be substantial. For example, with the retail price of 60 capsules of Apriso ranging from $180 to $190, a 75% discount would reduce the cost to approximately $45 to $47.50 for the same quantity.

Patient Assistance Programs

Patient assistance programs represent another avenue for reducing the cost of Apriso. These programs are typically offered by pharmaceutical companies, non-profit organizations, or government agencies and are designed to help patients who cannot afford their medications.

According to the available information, NowPatient offers several programs that can help lower the cost of Apriso prescriptions. After creating a free account with NowPatient, patients can access these programs from their account dashboard. Each program has clear instructions on checking eligibility, and some require completing an eligibility quiz.

The availability of these programs depends on the patient's insurance status:

For patients with federal, state, or government insurance: Rx Advantage Card and Canadian Prescription Savings are available. Patient Assistance Programs are available if offered by the pharmaceutical company.
For patients with commercial or private insurance: Rx Advantage Card and Canadian Prescription Savings are available. Drug Coupons and Patient Assistance Programs are available if offered by the pharmaceutical company.
For uninsured patients: Rx Advantage Card and Canadian Prescription Savings are available. Patient Assistance Programs are available if offered by the pharmaceutical company.

Patient assistance programs may provide medications at no cost or significantly reduced prices, depending on the specific program and the patient's financial circumstances. These programs often have eligibility requirements based on income, insurance status, and other factors.

Pharmacy Discount Coupons

When manufacturer offers and patient assistance programs are not available or sufficient, pharmacy discount coupons can provide an alternative way to reduce medication costs. These coupons are typically free and can be used regardless of insurance status.

According to the source material, free pharmacy coupons or cards are available that can provide instant discounts on prescriptions, including Apriso. These coupons are described as having no enrollment forms or membership fees and can be used unlimitedly on all prescriptions.

The savings from these coupons can vary depending on the specific pharmacy and medication. Some coupons may offer percentage discounts, while others provide fixed dollar amounts off the retail price. These coupons can be particularly beneficial for patients without insurance or those whose insurance does not cover Apriso.

To access these pharmacy discount coupons, patients typically need to visit a coupon provider's website and search for their specific medication. After finding the coupon for Apriso, they can print it out or show it on their phone at the pharmacy when filling their prescription.

Eligibility and Application Process

The eligibility requirements and application processes for Apriso cost-saving options vary depending on the specific program or coupon:

Manufacturer Coupons:
- Typically require enrollment through the manufacturer's website
- May have specific eligibility requirements based on insurance status
- Some programs may have ended or be temporarily unavailable
Discount Cards:
- Generally available to everyone regardless of insurance status
- Simple enrollment process, often requiring only basic information
- No income or insurance verification typically required
Patient Assistance Programs:
- Eligibility varies by program but often based on income and insurance status
- May require documentation of financial need
- Some programs are insurance-specific (e.g., only for uninsured patients)
Pharmacy Discount Coupons:
- Typically available to everyone with no eligibility requirements
- No enrollment or registration usually required
- Can be accessed immediately through coupon provider websites

When applying for any cost-saving program, patients should carefully review the terms and conditions to understand exactly what is covered and any limitations that may apply. It's also important to note that some programs may require patients to switch to a generic version of the medication if one is available.

Conclusion

While the provided source material does not specifically mention free samples of Apriso medication, there are several cost-saving options available to help make this prescription more affordable. Manufacturer coupons, discount cards, patient assistance programs, and pharmacy discount coupons can all provide significant savings on Apriso costs.

The most appropriate cost-saving option depends on the patient's specific circumstances, including their insurance coverage, income level, and eligibility for various programs. Patients are encouraged to explore multiple options to find the most cost-effective solution for their medication needs.

It's important to note that some manufacturer offers may have ended or be temporarily unavailable, so patients should check the most current information before applying. Additionally, eligibility requirements and terms may change, so verifying details before enrollment is recommended.

For those who continue to face financial challenges affording Apriso even with these cost-saving options, discussing alternatives with their healthcare provider may be beneficial. There may be other medications with similar efficacy but lower costs, or the provider may have additional resources to suggest.