Xifaxan Patient Assistance And Savings Programs For Cost-Access

Oct. 13, 2025, 5:54 p.m.

Tags: xifaxan

Xifaxan (rifaximin) is a medication used to treat certain gastrointestinal conditions, and patients seeking access to this treatment may find assistance through various programs designed to reduce financial barriers. The provided information outlines several options for obtaining Xifaxan at reduced costs, including patient assistance programs and copay savings initiatives. While traditional free samples are not explicitly mentioned, these programs offer alternative pathways to affordable access for eligible patients.

About Xifaxan

Xifaxan is an antibiotic medication primarily prescribed for three main conditions: traveler's diarrhea (TD), hepatic encephalopathy in adults, and irritable bowel syndrome with diarrhea (IBS-D). The medication works by stopping bacterial growth in the intestines, distinguishing it from many other antibiotics as it remains primarily in the gut with minimal absorption into the bloodstream.

The medication is administered orally in tablet form, available in 200 mg and 550 mg strengths. Patients may take Xifaxan with or without food as directed by their healthcare provider. The specific dosing varies depending on the condition being treated:

For traveler's diarrhea: 200 mg three times daily for three days at symptom onset
For hepatic encephalopathy: 550 mg twice daily for as long as prescribed
For IBS-D: 550 mg three times daily for 14 days, with potential for up to two additional courses within a six-month period

Like all medications, Xifaxan may cause side effects. Common side effects include nausea, dizziness, fatigue, and fluid retention. More serious but less common side effects may include severe allergic reactions, Clostridium difficile-associated diarrhea, and liver problems. The medication is contraindicated in patients with hypersensitivity to rifaximin, rifamycin antimicrobial agents, or any components of Xifaxan.

Patient Assistance Programs

The Rx Advocates offers a patient assistance program that helps eligible patients access Xifaxan at reduced costs. This program is designed to help patients regardless of income or insurance status by handling application processes and coordinating with manufacturers to ensure continuous medication access.

The program operates on a monthly fee structure: - One medication (Xifaxan only) - $80 per month - Two medications (Xifaxan plus one other) - $90 per month - Three medications (Xifaxan plus two others) - $100 per month - Four or more medications - $110 per month

Notably, there are no hidden fees, and prices remain consistent even if retail costs fluctuate. The Rx Advocates partners with over 100 pharmaceutical manufacturers and helps patients access assistance programs for more than 800 FDA-approved medications, including those in the top 100 prescribed by doctors in the United States.

Without patient assistance, the cost of Xifaxan can vary significantly based on several factors: - Dosage (200 mg or 550 mg tablets) - Geographic location - Specific pharmacy - Insurance coverage status

Copay Savings Program

Xifaxan offers an Instant Savings Card program for eligible, commercially insured patients. This program helps reduce out-of-pocket costs for patients with commercial insurance coverage. The savings card can be downloaded or activated online, though specific details about the potential savings amount are not provided in the source material.

Eligibility for the Instant Savings Card has specific restrictions: - Patients must be enrolled in a commercial insurance plan - The offer excludes full-cash-paying patients - Patients cannot participate in, seek reimbursement from, or submit claims to any federal or state healthcare program with prescription drug coverage (such as Medicaid, Medicare, Medigap, VA, DOD, TRICARE, or similar programs) - The offer cannot be used where prohibited by law

Maximum benefits and other restrictions apply, and patients are encouraged to visit the program website or call the manufacturer for complete eligibility criteria, terms, and conditions.

Eligibility Requirements

For The Rx Advocates patient assistance program, typical requirements include income-based eligibility: - Individual households with annual income up to $40,000 - Couples with annual income up to $60,000 - Larger families with annual income up to $100,000

Additionally, applicants must be U.S. residents with a valid prescription for Xifaxan. The program reviews individual information to determine qualification, and eligibility may be assessed on a case-by-case basis.

The Rx Advocates emphasizes that their services come with no hidden fees or additional costs beyond the monthly fee structure. They handle application processes, coordinate with healthcare providers, and manage manufacturer submissions on behalf of patients.

How to Apply

For The Rx Advocates program, patients can reach out to determine if they meet the guidelines and begin the application process. The program handles the entire application process, including coordination with healthcare providers and manufacturer submissions. Contact information is not explicitly provided in the source material, though patients are encouraged to "reach out" to determine eligibility.

For the Xifaxan Copay Savings Program, patients can download or activate the Instant Savings Card through the program website. Alternatively, they may call 1-866-XIFAXAN for assistance with the savings card and to verify eligibility. The program website (https://xifaxan.copaysavingsprogram.com) provides additional information about the terms and conditions.

Additional resources are available through the Xifaxan website, which includes materials to help patients understand treatment with Xifaxan and keep track of their IBS-D symptoms. The website also offers a video library with educational content about the medication.

Conclusion

While traditional free samples of Xifaxan are not explicitly mentioned in the provided source material, several assistance programs are available to help patients access this medication at reduced costs. The Rx Advocates offers a patient assistance program with a monthly fee structure that helps eligible patients obtain Xifaxan regardless of income or insurance status. Additionally, the Xifaxan Copay Savings Program provides copay assistance for eligible commercially insured patients.

Eligibility for these programs varies, with income requirements for the patient assistance program and insurance coverage requirements for the savings card. Patients interested in these programs should contact the respective programs directly for complete information and to determine their eligibility.

For healthcare providers, additional resources are available through the Xifaxan website, including dosing information, insurance requirements, and patient education materials. These resources can help providers better support their patients in accessing Xifaxan when appropriate.